Preventive Health in England: Simulation Study Reveals Long-Term Gains Against Chronic Illness (2025)

A groundbreaking simulation study has revealed the long-term benefits of preventive health policies in England, emphasizing the potential to significantly reduce the burden of chronic illnesses. Researchers from the University of Liverpool, in collaboration with The Health Foundation, analyzed anonymized health data from 1.5 million people to understand the impact of everyday health behaviors on long-term health. Their findings highlight the potential for substantial improvements in population health over the next two decades and beyond.

The study, published in Nature Communications, reveals a concerning trend: an increasing number of people in England are living with multiple long-term conditions such as heart disease, diabetes, and cancer. This trend is expected to persist as the population ages, posing a significant challenge to the National Health Service (NHS) and the quality of life for individuals. However, the study offers a glimmer of hope, demonstrating that improving health behaviors and reducing health risks can effectively reverse these trends.

Key findings from the study include:

  • Obesity (measured by BMI), smoking, and high blood pressure are the primary contributors to the rising prevalence of major long-term illnesses.
  • In an optimistic scenario where all risk factors are optimized, the model predicts a remarkable reduction in illness prevalence by 2043, preventing or delaying over five million years of major illness.
  • This improvement is further enhanced by a significant increase in the number of people living without major illness, resulting in 2.1 million more healthy lives in 2043.
  • Even modest improvements in risk factors can have a measurable impact, preventing or postponing around one million years lived with illness and reducing prevalence by 0.3 percentage points.
  • Health improvements will continue to grow beyond 2043, emphasizing the long-term benefits of preventive measures.
  • The benefits of these changes will not be evenly distributed, with obesity reduction having the most significant impact in disadvantaged communities, while lowering blood pressure will be more beneficial in wealthier areas.
  • Researchers caution that population health is a complex system, and some individuals may experience longer lifespans with pre-existing illnesses in the short term.

The study emphasizes the need for bold public health policies, particularly in reducing obesity and smoking, to alleviate future healthcare strain and support healthier lives for all. Dr. Chris Kypridemos, a Senior Lecturer in Public Health, Policy & Systems at the University of Liverpool, underscores the importance of society-wide policies to address the root causes of poor health and reduce pressure on the healthcare system.

Dr. Anna Head, a Research Fellow in Public Health, Policy & Systems, and Dr. Toby Watt, the lead economist at the Health Foundation, both emphasize the scale of the challenge and the need for ambitious action to support primary prevention efforts and address health inequalities. They highlight the potential for effective prevention to prevent millions of cases of serious illness and keep people in the workforce longer.

The research team is now conducting further analysis of real-world policy options, considering both health and economic outcomes. This work will incorporate newer data, such as post-pandemic trends, to design practical, long-term strategies for a healthier future.

Preventive Health in England: Simulation Study Reveals Long-Term Gains Against Chronic Illness (2025)
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